Carprofen inhibits the release of matrix metalloproteinases 1, 3, and 13 in the secretome of an explant model of articular cartilage stimulated with interleukin 1β

INTRODUCTION: Arthritic diseases are characterized by the degradation of collagenous and noncollagenous extracellular matrix (ECM) components in articular cartilage. The increased expression and activity of matrix metalloproteinases (MMPs) is partly responsible for cartilage degradation. This study...

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Detalhes bibliográficos
Main Authors: Williams, Adam, Smith, Julia R, Allaway, David, Harris, Pat, Liddell, Susan, Mobasheri, Ali
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978949/
https://ncbi.nlm.nih.gov/pubmed/24373218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4424
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