Association analysis of the SLC22A11 (organic anion transporter 4) and SLC22A12 (urate transporter 1) urate transporter locus with gout in New Zealand case-control sample sets reveals multiple ancestral-specific effects

INTRODUCTION: There is inconsistent association between urate transporters SLC22A11 (organic anion transporter 4 (OAT4)) and SLC22A12 (urate transporter 1 (URAT1)) and risk of gout. New Zealand (NZ) Māori and Pacific Island people have higher serum urate and more severe gout than European people. Th...

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Main Authors: Flynn, Tanya J, Phipps-Green, Amanda, Hollis-Moffatt, Jade E, Merriman, Marilyn E, Topless, Ruth, Montgomery, Grant, Chapman, Brett, Stamp, Lisa K, Dalbeth, Nicola, Merriman, Tony R
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978909/
https://ncbi.nlm.nih.gov/pubmed/24360580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4417
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