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B lymphocytes and B-cell activating factor promote collagen and profibrotic markers expression by dermal fibroblasts in systemic sclerosis

INTRODUCTION: B lymphocytes might play a pathogenic role in dermal fibrosis in systemic sclerosis (SSc). B-cell activating factor (BAFF), a key cytokine for B-cell activation, is increased in the serum and the skin of patients with SSc. However, the ability of B cells directly to stimulate dermal fi...

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Bibliografski detalji
Glavni autori: François, Antoine, Chatelus, Emmanuel, Wachsmann, Dominique, Sibilia, Jean, Bahram, Seiamak, Alsaleh, Ghada, Gottenberg, Jacques-Eric
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978899/
https://ncbi.nlm.nih.gov/pubmed/24289101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4352
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