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Inhibition of platelet aggregation by a monoclonal antibody against human fibronectin.

A monoclonal antibody (A3.3) has been generated against human platelet fibronectin (FN). A3.3 reacts with human plasma FN but with no other plasma proteins. A3.3 was found to inhibit thrombin- or ionophore A23187-stimulated aggregation of gel-filtered platelets in a concentration-dependent manner in...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Dixit, V M, Haverstick, D M, O'Rourke, K, Hennessy, S W, Broekelmann, T J, McDonald, J A, Grant, G A, Santoro, S A, Frazier, W A
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1985
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397884/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2582428/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.11.3844
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