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Thrombospondin-1, a natural inhibitor of angiogenesis, regulates platelet-endothelial cell adhesion molecule-1 expression and endothelial cell morphogenesis.

Expression of thrombospondin-1 (TS1) in polyoma middle-sized T (tumor)-transformed mouse brain endothelial cells (bEND.3) restores a normal phenotype and suppresses their ability to form hemangiomas in mice. We show that TS1 expression results in complete suppression of platelet-endothelial cell adh...

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Publicat a:Mol Biol Cell
Autors principals: Sheibani, N, Newman, P J, Frazier, W A
Format: Artigo
Idioma:Inglês
Publicat: American Society for Cell Biology 1997
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC276156/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9243511/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.8.7.1329
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