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Encounter complexes and dimensionality reduction in protein–protein association
An outstanding challenge has been to understand the mechanism whereby proteins associate. We report here the results of exhaustively sampling the conformational space in protein–protein association using a physics-based energy function. The agreement between experimental intermolecular paramagnetic...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3978769/ https://ncbi.nlm.nih.gov/pubmed/24714491 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.01370 |
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