Induction of nerve growth factor expression and release by mechanical and inflammatory stimuli in chondrocytes: possible involvement in osteoarthritis pain

INTRODUCTION: Nerve growth factor (NGF) level is increased in osteoarthritis (OA) joints and is involved in pain associated with OA. Stimuli responsible for NGF stimulation in chondrocytes are unknown. We investigated whether mechanical stress and proinflammatory cytokines may influence NGF synthesi...

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Main Authors: Pecchi, Emilie, Priam, Sabrina, Gosset, Marjolaine, Pigenet, Audrey, Sudre, Laure, Laiguillon, Marie-Charlotte, Berenbaum, Francis, Houard, Xavier
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2014
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978639/
https://ncbi.nlm.nih.gov/pubmed/24438745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4443
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