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Intra-tumor heterogeneity: lessons from microbial evolution and clinical implications

Multiple subclonal populations of tumor cells can coexist within the same tumor. This intra-tumor heterogeneity will have clinical implications and it is therefore important to identify factors that drive or suppress such heterogeneous tumor progression. Evolutionary biology can provide important in...

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Detalhes bibliográficos
Main Authors: de Bruin, Elza C, Taylor, Tiffany B, Swanton, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978608/
https://ncbi.nlm.nih.gov/pubmed/24267946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm505
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