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Intra-tumor heterogeneity of cancer cells and its implications for cancer treatment

Recent studies have revealed extensive genetic and non-genetic variation across different geographical regions of a tumor or throughout different stages of tumor progression, which is referred to as intra-tumor heterogeneity. Several causes contribute to this phenomenon, including genomic instabilit...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Sun, Xiao-xiao, Yu, Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648179/
https://ncbi.nlm.nih.gov/pubmed/26388155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2015.92
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