Decreased expression of the endothelial cell-derived factor EGFL7 in systemic sclerosis: potential contribution to impaired angiogenesis and vasculogenesis

INTRODUCTION: Microvascular damage and defective angiogenesis and vasculogenesis have a major role in the pathogenesis of systemic sclerosis (SSc). Epidermal growth factor-like domain 7 (EGFL7) is a proangiogenic molecule which is predominantly expressed and secreted by endothelial cells and their p...

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Bibliographic Details
Main Authors: Manetti, Mirko, Guiducci, Serena, Romano, Eloisa, Avouac, Jérôme, Rosa, Irene, Ruiz, Barbara, Lepri, Gemma, Bellando-Randone, Silvia, Ibba-Manneschi, Lidia, Allanore, Yannick, Matucci-Cerinic, Marco
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978601/
https://ncbi.nlm.nih.gov/pubmed/24286167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4349
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