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Lessons from Genome-Wide Search for Disease-Related Genes with Special Reference to HLA-Disease Associations

The relationships between diseases and genetic factors are by no means uniform. Single-gene diseases are caused primarily by rare mutations of specific genes. Although each single-gene disease has a low prevalence, there are an estimated 5000 or more such diseases in the world. In contrast, multifac...

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Detalhes bibliográficos
Autor principal: Tokunaga, Katsushi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978513/
https://ncbi.nlm.nih.gov/pubmed/24705288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes5010084
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