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Non-site-specific allosteric effect of oxygen on human hemoglobin under high oxygen partial pressure
Protein allostery is essential for vital activities. Allosteric regulation of human hemoglobin (HbA) with two quaternary states T and R has been a paradigm of allosteric structural regulation of proteins. It is widely accepted that oxygen molecules (O(2)) act as a “site-specific” homotropic effector...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3978498/ https://ncbi.nlm.nih.gov/pubmed/24710521 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep04601 |
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