Synthesis and Preliminary Evaluation of a 2-Oxoquinoline Carboxylic Acid Derivative for PET Imaging the Cannabinoid Type 2 Receptor

Cannabinoid receptor subtype 2 (CB2) has been shown to be up-regulated in activated microglia and therefore plays an important role in neuroinflammatory and neurodegenerative diseases such as multiple sclerosis, amyotrophic lateral sclerosis and Alzheimer’s disease. The CB2 receptor is therefore con...

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Main Authors: Mu, Linjing, Slavik, Roger, Müller, Adrienne, Popaj, Kasim, Čermak, Stjepko, Weber, Markus, Schibli, Roger, Krämer, Stefanie D., Ametamey, Simon M.
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2014
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978495/
https://ncbi.nlm.nih.gov/pubmed/24662272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph7030339
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