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Clinicopathologic assessment and imaging of tauopathies in neurodegenerative dementias

Microtubule-associated protein tau encoded by the MAPT gene binds to microtubules and is important for maintaining neuronal morphology and function. Alternative splicing of MAPT pre-mRNA generates six major tau isoforms in the adult central nervous system resulting in tau proteins with three or four...

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Detalhes bibliográficos
Main Authors: Murray, Melissa E, Kouri, Naomi, Lin, Wen-Lang, Jack, Clifford R, Dickson, Dennis W, Vemuri, Prashanthi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978456/
https://ncbi.nlm.nih.gov/pubmed/24382028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/alzrt231
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