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Immunoelectron Microscopic and Biochemical Studies of Caspase-Cleaved Tau in a Mouse Model of Tauopathy

Neurofibrillary tangles (NFTs) have been implicated in mediating neuronal death and disease progression in human tauopathies; however, mounting in vivo data suggest that NFTs may not be the primary initiators of neurotoxicity. Caspase activity has been implicated in processes associated with the dev...

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Bibliografiske detaljer
Main Authors: Lin, Wen-Lang, Dickson, Dennis W., Sahara, Naruhiko
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162471/
https://ncbi.nlm.nih.gov/pubmed/21865886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0b013e31822ac9c9
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