Autoantibodies to angiotensin and endothelin receptors in systemic sclerosis induce cellular and systemic events associated with disease pathogenesis

INTRODUCTION: Vasculopathy, inflammatory fibrosis and functional autoantibodies (Abs) are major manifestations of systemic sclerosis (SSc). Abs directed against the angiotensin II type 1 receptor (AT(1)R) and endothelin-1 type A receptor (ET(A)R) are associated with characteristic disease features i...

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Detalhes bibliográficos
Main Authors: Kill, Angela, Tabeling, Christoph, Undeutsch, Reinmar, Kühl, Anja A, Günther, Jeannine, Radic, Mislav, Becker, Mike O, Heidecke, Harald, Worm, Margitta, Witzenrath, Martin, Burmester, Gerd-Rüdiger, Dragun, Duska, Riemekasten, Gabriela
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978438/
https://ncbi.nlm.nih.gov/pubmed/24472528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4457
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