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T cell–derived interleukin (IL)-21 promotes brain injury following stroke in mice
T lymphocytes are key contributors to the acute phase of cerebral ischemia reperfusion injury, but the relevant T cell–derived mediators of tissue injury remain unknown. Using a mouse model of transient focal brain ischemia, we report that IL-21 is highly up-regulated in the injured mouse brain afte...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3978271/ https://ncbi.nlm.nih.gov/pubmed/24616379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20131377 |
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