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CCR2-dependent dendritic cell accumulation in CNS during early effector EAE is essential for effector T cell restimulation in situ and disease progression

Dendritic cells (DCs)—while absent from the healthy CNS parenchyma—rapidly accumulate within brain and spinal cord tissue during neuroinflammation associated with experimental autoimmune encephalomyelitis (EAE, a mouse model of multiple sclerosis). Yet, while DCs have been appreciated for their role...

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Podrobná bibliografie
Vydáno v:J Immunol
Hlavní autoři: Clarkson, Benjamin D, Walker, Alec, Harris, Melissa G., Rayasam, Aditya, Sandor, Matyas, Fabry, Zsuzsanna
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362728/
https://ncbi.nlm.nih.gov/pubmed/25505278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401320
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