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CCR2-dependent dendritic cell accumulation in CNS during early effector EAE is essential for effector T cell restimulation in situ and disease progression

Dendritic cells (DCs)—while absent from the healthy CNS parenchyma—rapidly accumulate within brain and spinal cord tissue during neuroinflammation associated with experimental autoimmune encephalomyelitis (EAE, a mouse model of multiple sclerosis). Yet, while DCs have been appreciated for their role...

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Bibliografiska uppgifter
I publikationen:J Immunol
Huvudupphovsmän: Clarkson, Benjamin D, Walker, Alec, Harris, Melissa G., Rayasam, Aditya, Sandor, Matyas, Fabry, Zsuzsanna
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362728/
https://ncbi.nlm.nih.gov/pubmed/25505278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401320
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