Lactaptin Induces p53-Independent Cell Death Associated with Features of Apoptosis and Autophagy and Delays Growth of Breast Cancer Cells in Mouse Xenografts

Lactaptin, the proteolytic fragment of human milk kappa-casein, induces the death of various cultured cancer cells. The mechanisms leading to cell death after lactaptin treatment have not been well characterized. In this study the in vivo and in vitro effects of a recombinant analogue of lactaptin (...

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Autori principali: Koval, Olga A., Tkachenko, Anastasiya V., Fomin, Alexandr S., Semenov, Dmitry V., Nushtaeva, Anna A., Kuligina, Elena V., Zavjalov, Eugeny L., Richter, Vladimir A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978064/
https://ncbi.nlm.nih.gov/pubmed/24710119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093921
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