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The N-Terminal Cleavage of Chondromodulin-I in Growth-Plate Cartilage at the Hypertrophic and Calcified Zones during Bone Development

Chondromodulin-I (ChM-I) is a 20–25 kDa anti-angiogenic glycoprotein in cartilage matrix. In the present study, we identified a novel 14-kDa species of ChM-I by immunoblotting, and purified it by immunoprecipitation with a newly raised monoclonal antibody against ChM-I. The N-terminal amino acid seq...

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Detalhes bibliográficos
Main Authors: Miura, Shigenori, Kondo, Jun, Takimoto, Aki, Sano-Takai, Hiroko, Guo, Long, Shukunami, Chisa, Tanaka, Hideyuki, Hiraki, Yuji
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977995/
https://ncbi.nlm.nih.gov/pubmed/24710035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094239
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