Synthetic disulfide-bridged cyclic peptides mimic the anti-angiogenic actions of chondromodulin-I

Chondromodulin-I (ChM-I) is a 25-kDa glycoprotein in cartilage matrix that inhibits angiogenesis. It contains two distinctive structural domains: the N-terminal third of the molecule is a hydrophilic domain that contains O-linked and N-linked oligosaccharide chains, and the C-terminal two-thirds is...

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Detalhes bibliográficos
Main Authors: Miura, Shigenori, Kondo, Jun, Kawakami, Toru, Shukunami, Chisa, Aimoto, Saburo, Tanaka, Hideyuki, Hiraki, Yuji
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3492907/
https://ncbi.nlm.nih.gov/pubmed/22429838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2012.02276.x
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