A frameshift mutation in the pre-S region of the human hepatitis B virus genome allows production of surface antigen particles but eliminates binding to polymerized albumin.

The coding region for the major polypeptide (p24S) of hepatitis B surface antigen (HBsAg) is preceded by an in-phase open reading frame termed pre-S. The coding potential of the pre-S region was examined in mouse L cells transformed with cloned hepatitis B virus DNA. Such cells produce three HBsAg-r...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Persing, D H, Varmus, H E, Ganem, D
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1985
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC397791/
https://ncbi.nlm.nih.gov/pubmed/3858831
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