Mitochondria directly donate their membrane to form autophagosomes during a novel mechanism of parkin-associated mitophagy

BACKGROUND: Autophagy (macroautophagy), a cellular process of “self-eating”, segregates damaged/aged organelles into vesicles, fuses with lysosomes, and enables recycling of the digested materials. The precise origin(s) of the autophagosome membrane is unclear and remains a critical but unanswered q...

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Main Authors: Cook, Katherine L, Soto-Pantoja, David R, Abu-Asab, Mones, Clarke, Pamela AG, Roberts, David D, Clarke, Robert
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2014
Assuntos:
Short Report
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977894/
https://ncbi.nlm.nih.gov/pubmed/24669863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-3701-4-16
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