Measuring Turnover of SIV DNA in Resting CD4+ T Cells Using Pyrosequencing: Implications for the Timing of HIV Eradication Therapies

Resting CD4+ T cells are a reservoir of latent HIV-1. Understanding the turnover of HIV DNA in these cells has implications for the development of eradication strategies. Most studies of viral latency focus on viral persistence under antiretroviral therapy (ART). We studied the turnover of SIV DNA r...

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Main Authors: Reece, Jeanette C., Martyushev, Alexey, Petravic, Janka, Grimm, Andrew, Gooneratne, Shayarana, Amaresena, Thakshila, De Rose, Robert, Loh, Liyen, Davenport, Miles P., Kent, Stephen J.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977820/
https://ncbi.nlm.nih.gov/pubmed/24710023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093330
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