Prepuberal Stimulation of 5-HT7-R by LP-211 in a Rat Model of Hyper-Activity and Attention-Deficit: Permanent Effects on Attention, Brain Amino Acids and Synaptic Markers in the Fronto-Striatal Interface

The cross-talk at the prefronto-striatal interface involves excitatory amino acids, different receptors, transducers and modulators. We investigated long-term effects of a prepuberal, subchronic 5-HT7-R agonist (LP-211) on adult behaviour, amino acids and synaptic markers in a model for Attention-De...

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Hauptverfasser: Ruocco, Lucia A., Treno, Concetta, Gironi Carnevale, Ugo A., Arra, Claudio, Boatto, Gianpiero, Nieddu, Maria, Pagano, Cristina, Illiano, Placido, Barbato, Fabiana, Tino, Angela, Carboni, Ezio, Laviola, Giovanni, Lacivita, Enza, Leopoldo, Marcello, Adriani, Walter, Sadile, Adolfo G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977819/
https://ncbi.nlm.nih.gov/pubmed/24709857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083003
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