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The brain-penetrant 5-HT(7) receptor agonist LP-211 reduces the sensory and affective components of neuropathic pain
Neuropathic pain is a debilitating pathological condition of high clinical relevance. Changes in neuronal excitability in the anterior cingulate cortex (ACC) play a central role in the negative emotional and affective aspects of chronic pain. We evaluated the effects of LP-211, a new serotonin-recep...
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| Pubblicato in: | Neurobiol Dis |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Academic Press
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5560654/ https://ncbi.nlm.nih.gov/pubmed/28690143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2017.07.005 |
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