Purification and Structural Study of the Voltage-Sensor Domain of the Human KCNQ1 Potassium Ion Channel

[Image: see text] KCNQ1 (also known as K(V)7.1 or K(V)LQT1) is a voltage-gated potassium channel modulated by members of the KCNE protein family. Among multiple functions, KCNQ1 plays a critical role in the cardiac action potential. This channel is also subject to inherited mutations that cause cert...

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Main Authors: Peng, Dungeng, Kim, Ji-Hun, Kroncke, Brett M., Law, Cheryl L., Xia, Yan, Droege, Kristin D., Van Horn, Wade D., Vanoye, Carlos G., Sanders, Charles R.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2014
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977583/
https://ncbi.nlm.nih.gov/pubmed/24606221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500102w
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