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Structural Basis of Mos1 Transposase Inhibition by the Anti-retroviral Drug Raltegravir
[Image: see text] DNA transposases catalyze the movement of transposons around genomes by a cut-and-paste mechanism related to retroviral integration. Transposases and retroviral integrases share a common RNaseH-like domain with a catalytic DDE/D triad that coordinates the divalent cations required...
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| 主要な著者: | , , , , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American
Chemical
Society
2014
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| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3977574/ https://ncbi.nlm.nih.gov/pubmed/24397848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb400791u |
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