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Use of mariner transposases for one-step delivery and integration of DNA in prokaryotes and eukaryotes by transfection

Delivery of DNA to cells and its subsequent integration into the host genome is a fundamental task in molecular biology, biotechnology and gene therapy. Here we describe an IP-free one-step method that enables stable genome integration into either prokaryotic or eukaryotic cells. A synthetic mariner...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Trubitsyna, Maryia, Michlewski, Gracjan, Finnegan, David J., Elfick, Alistair, Rosser, Susan J., Richardson, Julia M., French, Christopher E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5449632/
https://ncbi.nlm.nih.gov/pubmed/28204586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx113
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