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ALK-driven tumors and targeted therapy: focus on crizotinib

Receptor tyrosine kinases have emerged as promising therapeutic targets for a diverse set of tumors. Overactivation of the tyrosine kinase anaplastic lymphoma kinase (ALK) has been reported in several types of malignancies such as anaplastic large cell lymphoma, inflammatory myofibroblastic tumor, n...

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Bibliografiske detaljer
Main Authors: Murga-Zamalloa, Carlos, Lim, Megan S
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977456/
https://ncbi.nlm.nih.gov/pubmed/24715763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/PGPM.S37504
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