A second tRNA binding site on elongation factor Tu is induced while the factor is bound to the ribosome.
Previously, we reported that the antibiotic kirromycin induces two tRNA-binding sites on the elongation factor Tu. The classical binding site (site I) binds aminoacyl-tRNA and, with much less affinity, deacylated tRNA. The kirromycin-induced site II binds aminoacyl-tRNA, peptidyl-tRNA, and deacylate...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
1985
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397745/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3923474/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.10.3212 |
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