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A second tRNA binding site on elongation factor Tu is induced while the factor is bound to the ribosome.

Previously, we reported that the antibiotic kirromycin induces two tRNA-binding sites on the elongation factor Tu. The classical binding site (site I) binds aminoacyl-tRNA and, with much less affinity, deacylated tRNA. The kirromycin-induced site II binds aminoacyl-tRNA, peptidyl-tRNA, and deacylate...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Van Noort, J M, Kraal, B, Bosch, L
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1985
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397745/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3923474/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.10.3212
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