Preliminary evaluation of factors associated with premature trial closure and feasibility of accrual benchmarks in phase III oncology trials

BACKGROUND: A major challenge for randomized phase III oncology trials is the frequent low rates of patient enrollment, resulting in high rates of premature closure due to insufficient accrual. PURPOSE: We conducted a pilot study to determine the extent of trial closure due to poor accrual, feasibil...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Schroen, Anneke T, Petroni, Gina R, Wang, Hongkun, Gray, Robert, Wang, Xiaofei F, Cronin, Walter, Sargent, Daniel J, Benedetti, Jacqueline, Wickerham, Donald L, Djulbegovic, Benjamin, Slingluff, Craig L
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977321/
https://ncbi.nlm.nih.gov/pubmed/20595245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774510374973
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge