Preliminary evaluation of factors associated with premature trial closure and feasibility of accrual benchmarks in phase III oncology trials

BACKGROUND: A major challenge for randomized phase III oncology trials is the frequent low rates of patient enrollment, resulting in high rates of premature closure due to insufficient accrual. PURPOSE: We conducted a pilot study to determine the extent of trial closure due to poor accrual, feasibil...

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Detaylı Bibliyografya
Asıl Yazarlar: Schroen, Anneke T, Petroni, Gina R, Wang, Hongkun, Gray, Robert, Wang, Xiaofei F, Cronin, Walter, Sargent, Daniel J, Benedetti, Jacqueline, Wickerham, Donald L, Djulbegovic, Benjamin, Slingluff, Craig L
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977321/
https://ncbi.nlm.nih.gov/pubmed/20595245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774510374973
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