Direct evidence for positive selection of skin, hair, and eye pigmentation in Europeans during the last 5,000 y

Pigmentation is a polygenic trait encompassing some of the most visible phenotypic variation observed in humans. Here we present direct estimates of selection acting on functional alleles in three key genes known to be involved in human pigmentation pathways—HERC2, SLC45A2, and TYR—using allele freq...

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Main Authors: Wilde, Sandra, Timpson, Adrian, Kirsanow, Karola, Kaiser, Elke, Kayser, Manfred, Unterländer, Martina, Hollfelder, Nina, Potekhina, Inna D., Schier, Wolfram, Thomas, Mark G., Burger, Joachim
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2014
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977302/
https://ncbi.nlm.nih.gov/pubmed/24616518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1316513111
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