Direct evidence for positive selection of skin, hair, and eye pigmentation in Europeans during the last 5,000 y

Pigmentation is a polygenic trait encompassing some of the most visible phenotypic variation observed in humans. Here we present direct estimates of selection acting on functional alleles in three key genes known to be involved in human pigmentation pathways—HERC2, SLC45A2, and TYR—using allele freq...

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Autori principali: Wilde, Sandra, Timpson, Adrian, Kirsanow, Karola, Kaiser, Elke, Kayser, Manfred, Unterländer, Martina, Hollfelder, Nina, Potekhina, Inna D., Schier, Wolfram, Thomas, Mark G., Burger, Joachim
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2014
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977302/
https://ncbi.nlm.nih.gov/pubmed/24616518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1316513111
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