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Decoupling catalytic activity from biological function of the ATPase that powers lipopolysaccharide transport

The cell surface of Gram-negative bacteria contains lipopolysaccharides (LPS), which provide a barrier against the entry of many antibiotics. LPS assembly involves a multiprotein LPS transport (Lpt) complex that spans from the cytoplasm to the outer membrane. In this complex, an unusual ATP-binding...

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Bibliografiske detaljer
Main Authors: Sherman, David J., Lazarus, Michael B., Murphy, Lea, Liu, Charles, Walker, Suzanne, Ruiz, Natividad, Kahne, Daniel
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977253/
https://ncbi.nlm.nih.gov/pubmed/24639492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1323516111
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