Sequence context effects in DNA replication blocks induced by aflatoxin B1.

The genotoxic effects of the potent mutagenic carcinogen aflatoxin B1 (AFB1) are believed to be mediated by its reaction with the N-7 atom of guanine residues in DNA. We have analyzed the effect of AFB1-induced chemical modification on the template function of single-stranded DNA in vitro. The exper...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Refolo, L M, Conley, M P, Sambamurti, K, Jacobsen, J S, Humayun, M Z
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1985
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397721/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3923472/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.10.3096
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