Sequence context effects in DNA replication blocks induced by aflatoxin B1.

The genotoxic effects of the potent mutagenic carcinogen aflatoxin B1 (AFB1) are believed to be mediated by its reaction with the N-7 atom of guanine residues in DNA. We have analyzed the effect of AFB1-induced chemical modification on the template function of single-stranded DNA in vitro. The exper...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Refolo, L M, Conley, M P, Sambamurti, K, Jacobsen, J S, Humayun, M Z
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1985
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397721/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3923472/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.10.3096
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