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Protein Disulfide Isomerase A6 controls the decay of IRE1α signaling via disulfide-dependent association
The response to endoplasmic reticulum (ER) stress relies on activation of unfolded protein response (UPR) sensors, and the outcome of the UPR depends on the duration and strength of signal. Here we demonstrate a novel mechanism that attenuates the activity of the UPR sensor inositol-requiring enzyme...
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| Main Authors: | , , , , |
|---|---|
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3977204/ https://ncbi.nlm.nih.gov/pubmed/24508390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.01.004 |
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