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M2 microglia/macrophages drive oligodendrocyte differentiation during CNS remyelination

The lack of therapies for progressive multiple sclerosis highlights the need to understand the regenerative process of remyelination that can follow CNS demyelination. This involves an innate immune response consisting of microglia/macrophages, which can be polarized to distinct functional phenotype...

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Hlavní autoři: Miron, Veronique E., Boyd, Amanda, Zhao, Jing-Wei, Yuen, Tracy J., Ruckh, Julia M., Shadrach, Jennifer L., van Wijngaarden, Peter, Wagers, Amy J., Williams, Anna, Franklin, Robin J.M., ffrench-Constant, Charles
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977045/
https://ncbi.nlm.nih.gov/pubmed/23872599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3469
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