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Fetal-specific DNA methylation ratio permits non-invasive prenatal diagnosis of trisomy 21

The trials performed worldwide towards Non-Invasive Prenatal Diagnosis (NIPD) of Down syndrome (or Trisomy 21) have demonstrated the great commercial and medical potential of NIPD compared to the currently used invasive prenatal diagnostic procedures. Extensive investigation of methylation differenc...

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Библиографические подробности
Главные авторы: Papageorgiou, Elisavet A., Karagrigoriou, Alex, Tsaliki, Evdokia, Velissariou, Voula, Carter, Nigel P., Patsalis, Philippos C.
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977039/
https://ncbi.nlm.nih.gov/pubmed/21378977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2312
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