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Fetal-specific DNA methylation ratio permits non-invasive prenatal diagnosis of trisomy 21

The trials performed worldwide towards Non-Invasive Prenatal Diagnosis (NIPD) of Down syndrome (or Trisomy 21) have demonstrated the great commercial and medical potential of NIPD compared to the currently used invasive prenatal diagnostic procedures. Extensive investigation of methylation differenc...

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Detalhes bibliográficos
Main Authors: Papageorgiou, Elisavet A., Karagrigoriou, Alex, Tsaliki, Evdokia, Velissariou, Voula, Carter, Nigel P., Patsalis, Philippos C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977039/
https://ncbi.nlm.nih.gov/pubmed/21378977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2312
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