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Visualization of Distinct Substrate Recruitment Pathways in the Yeast Exosome by Electron Microscopy
The eukaryotic exosome is a multi-subunit complex typically composed of a catalytically inactive core and the Rrp44 protein, which contains 3’ to 5’ exo- and endo-ribonuclease activities. RNA substrates have been shown to be recruited through the core to reach Rrp44's exoribonuclease (EXO) site...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3976988/ https://ncbi.nlm.nih.gov/pubmed/24336220 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2736 |
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