Hybrid molecules containing the B-domain of insulin-like growth factor I are recognized by carrier proteins of the growth factor.

The insulin-like growth factors (IGFs) are polypeptides in plasma that are chemically related to insulin and have mitogenic and insulin-like activity. Unlike insulin, the IGFs circulate in plasma bound to specific high molecular weight carrier proteins that regulate their delivery to target tissues....

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: De Vroede, M A, Rechler, M M, Nissley, S P, Joshi, S, Burke, G T, Katsoyannis, P G
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1985
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397696/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2581261/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.9.3010
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