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Modulation of insulinlike growth factor I binding to human fibroblast monolayer cultures by insulinlike growth factor carrier proteins released to the incubation media.

The relative contributions of type I and type II insulinlike growth factor (IGF) receptors and IGF carrier proteins to the binding of IGF-I tracer to cultured human fibroblasts were determined in competitive binding experiments that used unlabeled insulin and synthetic insulin-IGF-I hybrid molecules...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: De Vroede, M A, Tseng, L Y, Katsoyannis, P G, Nissley, S P, Rechler, M M
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1986
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423394/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2418066/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112343
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