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Essential role of phospholipase A2 activity in endothelial cell-induced modification of low density lipoprotein.

Previous studies have established that incubation of low density lipoprotein (LDL) with cultured endothelial cells (EC) converts it to a new form (EC-modified LDL) that is now recognized by a specific receptor on macrophages (the acetyl LDL receptor) and is taken up and degraded 3-10 times more rapi...

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Main Authors: Parthasarathy, S, Steinbrecher, U P, Barnett, J, Witztum, J L, Steinberg, D
格式: Artigo
語言:Inglês
出版: 1985
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC397694/
https://ncbi.nlm.nih.gov/pubmed/3857630
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