Association of P2Y12 Gene Promoter DNA Methylation with the Risk of Clopidogrel Resistance in Coronary Artery Disease Patients

Background. Clopidogrel inhibits the ADP receptor P2Y12 to keep down the platelet aggregation. The goal of our study is to investigate the contribution of P2Y12 promoter DNA methylation to the risk of clopidogrel resistance (CR). Methods. The platelet functions were measured by the VerifyNow P2Y12 a...

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Main Authors: Su, Jia, Li, Xiaojing, Yu, Qinglin, Liu, Yahui, Wang, Yaqing, Song, Haojun, Cui, Hanbin, Du, Weiping, Fei, Xiaohong, Liu, Junsong, Lin, Shaoyi, Wang, Jian, Zheng, Wenyuan, Zhong, Jinyan, Zhang, Lulu, Tong, Maoqing, Xu, Jin, Chen, Xiaomin
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3976931/
https://ncbi.nlm.nih.gov/pubmed/24745016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/450814
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