Association of P2Y12 Gene Promoter DNA Methylation with the Risk of Clopidogrel Resistance in Coronary Artery Disease Patients

Background. Clopidogrel inhibits the ADP receptor P2Y12 to keep down the platelet aggregation. The goal of our study is to investigate the contribution of P2Y12 promoter DNA methylation to the risk of clopidogrel resistance (CR). Methods. The platelet functions were measured by the VerifyNow P2Y12 a...

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Autors principals: Su, Jia, Li, Xiaojing, Yu, Qinglin, Liu, Yahui, Wang, Yaqing, Song, Haojun, Cui, Hanbin, Du, Weiping, Fei, Xiaohong, Liu, Junsong, Lin, Shaoyi, Wang, Jian, Zheng, Wenyuan, Zhong, Jinyan, Zhang, Lulu, Tong, Maoqing, Xu, Jin, Chen, Xiaomin
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2014
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3976931/
https://ncbi.nlm.nih.gov/pubmed/24745016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/450814
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