Mitochondrial function and energy metabolism in neuronal HT22 cells resistant to oxidative stress

BACKGROUND AND PURPOSE: The hippocampal cell line HT22 is an excellent model for studying the consequences of endogenous oxidative stress. Extracellular glutamate depletes cellular glutathione by blocking the glutamate/cystine antiporter system xc−. Glutathione depletion induces a well-defined progr...

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Bibliographische Detailangaben
Hauptverfasser: Pfeiffer, Annika, Jaeckel, Martin, Lewerenz, Jan, Noack, Rebecca, Pouya, Alireza, Schacht, Teresa, Hoffmann, Christina, Winter, Jennifer, Schweiger, Susann, Schäfer, Michael K E, Methner, Axel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 2014
Schlagworte:
Themed Issue: Mitochondrial Pharmacology: Energy, Injury & Beyond
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3976627/
https://ncbi.nlm.nih.gov/pubmed/24319993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12549
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