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Turn up the power –pharmacological activation of mitochondrial biogenesis in mouse models

The oxidative phosphorylation (OXPHOS) system in mitochondria is responsible for the generation of the majority of cellular energy in the form of ATP. Patients with genetic OXPHOS disorders form the largest group of inborn errors of metabolism. Unfortunately, there is still a lack of efficient thera...

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Autori principali: Komen, J C, Thorburn, D R
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3976607/
https://ncbi.nlm.nih.gov/pubmed/24102298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12413
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